The general description of the chemical industry enterprises in the Western region is given. The paper reveals that the main part of the chemical industry enterprises of the region accounts for the enterprises producing basic chemical products, fertilizers and nitrogen compounds, plastics and synthetic rubber in primary forms (40%). The largest chemical enterprises are: LLC «Karpatnaftokhim» – the only Ukrainian producer of ethylene, propylene, benzene, C9 fractions, polyethylene, as well as caustic soda and suspension polyvinyl chloride; PJSC «Rivneazot» is one of the largest producers of mineral fertilizers and adipic acid in Ukraine. Their share in the volume of sold chemicals and chemical products in the region is about 87%. A general description of the activity of these enterprises is given. The activity of the chemical industry enterprises of the developing region is described: LLC «KarpatSmoly» is one of the largest manufacturers of low-toxic resins in Ukraine (U-type carbamide-formaldehyde resins of types E-1, ? E-1 and E-0 and melamine resins UMF, MUF, MF); Polikom Ltd. – is engaged in the development of compositions based on PVC, the production of commercial PVC-plastisols and decorative granulates for the production of wallpaper, linoleum, artificial leather, LLC Polikem – produces plasticizers of five types (dioctyl phthalate, dioctyladipinate, diisodecyladipinate, dibutylmalainate, dizononyl phthalate); Zhivitsa Plus Ltd – specializes in the production of low-toxic aminometallergic resins; PJSC «Lviv Chemical Plant» is the only producer of technical gases in the Western Ukraine. The basic problems of the development of chemical industry enterprises in the Western region are revealed, in particular: environmental problems, the need to promote the development of raw materials, the organization of new industries and others. In order to provide more efficient work of chemical industry enterprises, it is proposed to gradually modernize equipment, introduce innovative technological processes, and apply more energy-saving methods of production. The fact that these measures will contribute to satisfying market demand, expanding the range of products and increasing the competitiveness of enterprises on the world market of chemical products is emphasized.