The article presents the current trends of business development on the principles of "Industry 4.0", identifies key challenges and opportunities for new innovative forms of spatial business organization. The unconditionality of the connection of industrial forms of spatial business organization with the processes of modern industrialization is substantiated, confirmed by the practical irreversible technological breakthrough of humanity. The main trends of the dynamics of growth of society digital potential are indicated. First of all, a key factor in the current dynamics of the development of socio-economic systems, namely, the dissemination of the Internet is indicated. Under modern conditions of management, the Internet is no longer seen as a luxury for rich and highly developed countries, but rather as one of the most powerful tools in the history of mankind to overcome poverty and gaps in health, education, and the protection of rights and freedoms. The article argues that the growth of digitalization scales should also be associated with the annual growth of data processing speed, as well as cheaper methods and tools for their storage. One of the factors contributing to the growth of the digital potential of humanity is the transformation of social development into the field of industrial Internet, which combines intelligent machines, advanced analytical tools and control, management, information processing and creativity centers. The article presents the key barriers to digital transformation: internal changes and human factors, lack of investors and insufficient synergies within local ecosystems. The main characteristics of the contribution of the industrial Internet to the world economy and the peculiarities of its distribution in Ukraine are presented. It is noted that the formation of an institutional model and strategy for the development of innovative industrial forms of spatial business organization in Ukraine should be carried out taking into account the current challenges and opportunities that are bearing the modern framework technological trends. Taking into account the exponential growth of innovations in the world to ensure the process of Ukraine's entry into the global high-tech market, the necessity of developing a national technological breakthrough has been emphasized. It also emphasized the need to initiate the creation at national and local levels of innovation, science, education, government and community platforms and innovative forms of spatial business organization to launch such a breakthrough. 

business, innovation, entrepreneurship, production processes, spatial forms of business