The regions’ position in national competitive ability and the rankings of a country in global competitive environment is defined by innovative vector of economy development, the level of economic entities’ innovative activity, availability of fundamental and applied developments, technology transfer and integration of science and production, etc. Therefore, the issues of maintaining the development of innovative entrepreneurship in a region as an important direction of economy’s competitive ability at internal and external markets are the most relevant. The paper aims to develop a methodological approach to evaluation of innovative entrepreneurship development in the regions of a country. A review of existing methodological approaches to the analysis and evaluation of the development of innovation entrepreneurship in the regions of the state is outlined. The author's vision of the methodology of analysis and evaluation of the development of innovation entrepreneurship of the regions of the state is presented. The proposed methodology contains the following structural elements: the choice of the objective, object and tasks of the assessment of the development of innovative entrepreneurship in the region, the choice of methods for assessing the development of innovative entrepreneurship in the region, the choice of directions for assessing the development of innovative entrepreneurship in the region (assessment of the stages of innovation business development in the region, assessment of forms of integration of innovation entrepreneurship, the estimation of entrepreneurial income), the choice of a system of indicators for assessing the development of innovative entrepreneurship in the region, a comprehensive assessment of the level of innovation entrepreneurship in the region. 

small business, business, causes, factors, development, national economy, problems, stages, activities