Crisis management is one of the strategically important elements for the sustainable development of agro-processing enterprises, which facilitates access to the best markets, improves business conditions and realization of the country's resource potential and strengthens the industrial relations between the divisions of the enterprise. The article reveals the essence of crisis management of agro-processing enterprises and the peculiarities of its formation in the sustainable development strategic program in the market environment. Imperfection of management decision making technologies was determined to be the reason for the emergence of crisis phenomena. The contradiction of tactical methods of providing economic stability of agro-processing enterprises in the current economic activity was found to be provoking the emergence of crisis phenomena. The main directions of reforming the mechanism of crisis management of agro-processing enterprises with the use of the advantages of multi-alternative economic models in the programming of sustainable development were determined. The mechanism of long-term programming of sustainable development in the dynamic market conditions based on the use of a business-friendly enterprise model was constructed. The analysis of alternatives of economic model development on the example of the meat processing enterprise and programming of optimal development management were conducted in order to ensure maximum profitability of the invested funds. The authors confirm that the measures of adaptation to the regional conditions of the market environment allow providing the corresponding efficiency of the product set of the enterprise. However, the lack of a new approach to crisis management with different tactical tasks in shaping the development strategy impedes the development of productive assets and reduces the efficiency of the investment process of the enterprise. The directions to enhance the system of crisis management of agro-processing enterprises were defined: development of poly-business model of development of agro-processing enterprises; introduction of long-term programming of effective development and updating of production and resource base; compliance with the norms of effective use of capital to the requirements of investment processes of Ukraine and the EU.