The article deals with the peculiarities of the formation of innovation-investment policy at industrial enterprises. The paper emphasizes the fact of the lack of institutional support of innovative activity of Ukrainian’s enterprises, which is the reason why there is a lack of a national innovation priorities concept and a systematic approach to the development of innovation activity. The requests of substantiation of optimal development models are investigated; the principles, forms, methods of implementation of innovation and investment development policy are defined; the parameters, principles, scientific and methodical foundations of creation of modern innovative forms of development are outlined; providing scientific support for development programs is emphasized. The connection of the implementation of innovations in the economic practice at industrial enterprises with innovative entrepreneurship, which depends on the speed of conducting of restructuring processes on the basis of construction innovation-investment model development of the economy, was proved. The basic tasks were defined, namely, first of all, the active use of human capital, scientific and technical potential of its realization; forming a competitive environment; providing real state support; setting up an efficient financial and banking systems, an efficient stock market; a well-established investment process, which in turn requires improvement of the corporate governance system of enterprises that provides for transparency of the ownership structure, provision of shareholders with high-quality and reliable information. The destabilizing factors of realization of innovation-investment potential at industrial enterprises, in particular, machine-building enterprises of Ukraine were defined, among them: insufficient development of solvent internal market of machine-building products, lack of state and regional development program, significant dependence on market conditions on foreign markets; general deficiencies in the implementation of the state program of development of mechanical engineering, shortages of personnel required qualification (scientific, technical, engineering, labor specialties), lack of state financial support, and, in particular state protection against raider attacks. The paper emphasizes that venture capital company should play a special role in realizing an innovation model of development, which will enable the increase of the complexity of production; the use of the existing productive assets to a greater extent, the expanding of the production infrastructure; the creation of the basis for the formation and development of new organizational forms and production activity; the realization of the social orientation of the industry development. The necessity of stimulating the development of socially significant productions, which allows solving problems of socio-economic development without increasing the ecological burden on the natural system, was determined. It is essential to develop and implement relevant investment programs on the basis of well-defined volumes of investment resources; to increase investment attractiveness at the expense of streamlining the market space for commodity producers; to create guarantees of protection of capital and income of investors. 

management, industrial potential, destabilization factors, development model, innovation and investment policy